Center for Drug Discovery and Innovation

Chemodiversity Facility

Agilent Mass Spectrometry GC-MS
Agilent 7890A GC-MS QToF 7200
Agilent 1200 LC-MS 6120B SQ
Teledyne-ISCO Torrent MPLC
Shimadzu HPLC (UV, ELSD)
Shimadzu HPLCs (UV, RID)
TECAN Freedom Evo 150
SP Scientific General Purpose Freeze-Dryer
Labconco Freezone 4.5L Lyophilizer
Heidolph Rotary Evaporator Valve Control Vacuum Pump
Microwave Reactor - Anton Paar Monowave 300
Labconco Fume Hood for Synthesis and Extraction Activities
Thermo Scientific 1300 A2 Biosafety Hoods
Agilent Cary FTIR 630 Spectrometer and Cary 60 UV/Vis Spectrophotometer
Thermmax -20C Walk-in Cold Room
Thermo Scientific -80C Freezer

Overview

The Chemodiversity facility offers libraries of natural product-derived crude extracts, fractions and pure compounds for screening as well as medicinal chemistry and hit-to-lead synthetic capabilities. Small molecules high resolution mass measurement, quantification and metabolomics (GC/MS QToF), mass targeted chromatographic separation (LC/MS SQ) and screening for anthelmintic, antimicrobial, permeability and drug solubility evaluation are provided. The services also include general chromatography (MPLC, HPLC) and spectroscopic characterization (UV, IR) as well as microbiology workspace (biosafety cabinets), training and synthesis activities.

Major Equipment and Instrumentation

Teledyne-Isco MPLC (UV) and Shimadzu HPLC (UV, ELSD, RID) systems
TECAN Freedom EVO 150 liquid handling automated workstation
Tecan Infinite/ M-1000 multimode plate reader
Heidolph control valve rotary evaporators, Savant SC210A speedvacuum concentrators
Labconco 4.5 Liters freeze dryer and SP Scientific general purpose 35 Liters freeze dryer
Agilent 7890 GC/ 7200 MS QToF
Agilent preparative 1200 LC/ 6120B MS SQ
Anton-Paar monowave reactor 300 for assisted microwave synthesis
Agilent Cary FTIR 630 spectrometer and Cary 60 UV/Vis spectrophotometer
Labconco synthetic fume hoods and Thermo scientific biosafety hoods
Innovative Technologies Pure Solv Micro solvent purification system for anhydrous solvent preparation

Poster Presentation

CDDI Chemodiversity Facility Poster (PDF)

Services Forms

Chemodiversity Facility Service Requisition (PDF)
New Customer Account Set-Up Form (PDF)

Location and Contact Information

Interdisciplinary Research (IDR) Building
3720 Spectrum Blvd., Suite 318
Tampa, Florida 33612
P: (813) 974-0112
E: cddi@usf.edu